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Peptides/Recovery and injury

TB-500

Also sold as Thymosin Beta-4, TB4

Usually sold alongside BPC-157 as a healing stack. Interesting biology, animal data, and no completed human trial for injury recovery.

Research onlyNo human trials
Photo by Direct Media · CC0 1.0 · source

At a glance

What people use it for

  • Soft tissue injuries, often stacked with BPC-157
  • Recovery from heavy training
  • Marketed for flexibility and range of movement

How it is taken

Sold as a powder for injection, usually reconstituted and injected under the skin.

Evidence

No human trials

Good to know

  • No completed human trial supports the injury recovery claims
  • Prohibited in sport as a non-approved substance
  • Its effect on blood vessel growth raises theoretical concerns for anyone with cancer
  • Unregulated supply, so contents and sterility are unverified

TB-500 is a synthetic version of part of thymosin beta-4, a protein your body makes that is involved in cell movement and wound repair. In practice it is sold as the partner to BPC-157, and the two are very often bought together.

What people take it for

Soft tissue injuries and general recovery. The pitch is that it helps cells migrate to the site of damage and encourages new blood vessels to form there, which is a plausible description of the biology.

What the evidence shows

The underlying protein is real and genuinely does the things described, in cell cultures and in animals. Thymosin beta-4 itself has been through human trials for eye surface injuries and for pressure ulcers, with mixed results.

What does not exist is a completed human trial showing that injecting TB-500 helps a torn hamstring or a stubborn tendon. That gap between real biology and demonstrated benefit is what the evidence badge on this page is describing.

What to know before

The blood vessel growth that makes it appealing for healing is the same reason it warrants caution for anyone with a cancer history. Tumours need blood supply. This is a theoretical concern rather than a documented harm, but it is the kind of theoretical concern that human trials exist to settle, and no such trial has been done.

It is banned in sport.

Last reviewed .