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Guides

Practical guides

The mechanical side: mixing a vial, choosing equipment, the injection procedure itself, and how to tell an ordinary bruise from something that needs a doctor. Written for people who have already decided, and read in order if you are starting from nothing.

Why this section exists

Describing a procedure is not recommending it. People who have decided to inject something will do so whether or not there is an accurate account of sterile technique available to them, and the difference between good technique and improvised technique is measured in abscesses. Nothing here argues that anyone should take any of the compounds this site covers, and most of them are not approved for human use anywhere.

Educational content only. Nothing here is medical advice, and most compounds discussed are not approved for human use. Talk to a clinician before acting on anything you read. Full disclaimer.

  1. 01

    How to reconstitute a peptide vial

    Turning a freeze-dried powder into a solution, and the handling details that decide whether the vial survives it.

    Covers

    • What lyophilised powder is and why it needs mixing
    • Bacteriostatic water against sterile water
    • How much diluent to add, and what that changes
    • The order of operations, and what ruins a vial

    7 min read · reviewed

  2. 02

    Choosing needles and syringes

    What the numbers on a syringe wrapper mean, and how to pick a barrel small enough to read the dose you are measuring.

    Covers

    • What gauge and length numbers mean
    • Insulin units against millilitres
    • Picking a barrel size for your dose
    • Coring, reuse and sharps disposal

    6 min read · reviewed

  3. 03

    Subcutaneous injection technique

    The standard procedure for a fat-layer injection, the sites it uses, and why rotating between them is not optional.

    Covers

    • Which sites are used, and which to avoid
    • Why site rotation prevents lipohypertrophy
    • The step-by-step procedure
    • Angles, pinching and needle length

    6 min read · reviewed

  4. 04

    Injection site problems and warning signs

    Telling an ordinary bruise from cellulitis, an abscess or an allergic reaction, and knowing which of them cannot wait.

    Covers

    • What is normal after an injection
    • Cellulitis, abscess and when to seek care
    • Lipohypertrophy and scarring
    • Allergic reactions and what an emergency looks like

    6 min read · reviewed

The calculator that goes with these

Once a vial is mixed, its concentration decides which mark on the syringe a dose falls on. The reconstitution calculator does that arithmetic and shows the fill level on the barrel.